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The Kidney Disease: Improving Global Outcomes (KDIGO) Clinical Practice Guidelines recommend confirmatory testing for estimated glomerular filtration rate (eGFR) using cystatin C or…
The intestinal microbiome has become a facet of human biology that is attracting great interest, including among investigators in the field of kidney disease. In CKD, “uremic” toxins may be…
The optimal management of ischemic coronary artery disease in patients with end-stage renal disease (ESRD) awaiting renal transplantation remains as a conundrum. Avoidance of a cardiovascular (CV) death following renal…
April 27, 2018
A Biomarker for Calcineurin Inhibitor Responsiveness in Primary Membranous Nephropathy
The ability to reliably and accurately predict the response to treatment of glomerular disease with specific regimens would be a great advance…
April 23, 2018
Substitution of Central Venous Blood Gas for Arterial Blood Gas for the Diagnosis of Acid-Base Disturbances?
Disturbances of acid-base homeostasis very commonly complicate critical illnesses. Arterial blood gases (ABG) combined with assessment of serum electrolytes (especially the anion gap and delta bicarbonate) are traditionally used…
Left ventricular hypertrophy (LVH) is common in chronic kidney disease (CKD) and in end-stage renal disease (ESRD) treated by dialysis. The failure of LVH to regress or its progression can…
In a very remarkable retrospective “registry-based” study, Hou and colleagues examined the changes in the spectrum of kidney disease derived from careful study of 40,759 native kidney biopsies…